| Gamme : | Family Health, Gynecology | ||
| Classe thérapeutique : | Quinolone | ||
| Fiche posologique : |
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Fiche RCP : |
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| Dosage : | A 400 mg tablet morning and evening. |
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| Emballage : | Pack of 10 tablets | ||
| Actions : | Quinolones act by formation of a ternary complex between DNA and DNA gyrase (topoisomerases II) (genes gyr A and gyr B) or topoisomerases IV (genes by C and E). These enzymes are directly involved in the disruption and supercoiling mechanisms of DNA during replication to facilitate the action of DNA polymerase. The antibacterial activity Gram - passes mainly by the inhibition of the DNA gyrase activities while the anti-Gram + activity seems to go through the blocking of the topoisomerase IV. |
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| Composition : | One tablet contains 400 mg pipemidic acid (as trihydrate) |
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| Indications : | Uncomplicated, acute or recurrent lower urinary tract infections in adults with sensitive germs. |
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